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Objective Gastric cancer(GC) is one of the most common malignant diseases and the second most frequent cause of cancer-related mortality worldwide.According to GLOBOCAN 2012 estimates,the incidence of GC in East Asia is the highest in the world.Although D2 surgery is well accepted as a standard of care for local-advanced gastric cancer(LAGC),local-regional recurrence remains the frequent mode of cancer relapse.