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5. Design and synthesis of boronic acid derivatives as inhibitors of metallo-β-lactamases

Design and synthesis of boronic acid derivatives as inhibitors of metallo-β-lactamases

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：filltang

【摘 要】

：

　　β-Lactamases catalyzed hydrolysis of β-lactam antibiotics,such as penicillins,cephalosporins,and carbapenems,and are the most widespread bacterial resista

【作 者】

：

Liwei Xu Kewu Yang 

【机 构】

：

KeyLaboratoryofSyntheticandNaturalFunctionalMoleculeChemistryofMinistryofEducation,CollegeofChemistr

【出 处】

：

中国化学会第十届全国化学生物学学术会议

【发表日期】

：

2017年9期

【关键词】

：

Metallo-β-lactamases Inhibitor Boronic acid 

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　　β-Lactamases catalyzed hydrolysis of β-lactam antibiotics,such as penicillins,cephalosporins,and carbapenems,and are the most widespread bacterial resistance mechanism to these drugs[1].

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