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  5. Isoform-specific regulation of AKT turn-motif phosphorylation and overall phosphorylation profiles

Isoform-specific regulation of AKT turn-motif phosphorylation and overall phosphorylation profiles

来源 :第四届广州国际肿瘤学会议 | 被引量 : 0次 | 上传用户：aoyun2000
【摘 要】
：
　　Aberrant AKT activation is prevalent across multiple human cancer lineages,providing an important target for therapy.Phosphorylation plays critical roles in
【作 者】
：
Sean Barnes Gordon B.Mills Meng Gao Zhiyong Ding Qinghua Yu Yiling Lu Huifang Guo Jiyong Liang Shanshan Bai Eric Jonasch Philip L.Lorenzi 
【机 构】
：
Departments of 1Systems Biology,UT MD Anderson Cancer Center,1515 Holcombe Blvd,Houston,TX 77030
【出 处】
：
第四届广州国际肿瘤学会议
【发表日期】
：
2015年期
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　　Aberrant AKT activation is prevalent across multiple human cancer lineages,providing an important target for therapy.Phosphorylation plays critical roles in AKT stability and activation.
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