Platelet-derived serotonin stimulates TPO released from bone marrow mesenchymal stromal cells in bot

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户:loveagle
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Objective The bone marrow (BM) microenvironment plays an important role in regulation of thrombopoiesis through release of thrombopoietic growth factor,among which thrombopoietin (TPO) is the most essential regulator.It has been realized that the TPO blood level and platelet count is inversely related,but the precise controlling mechanism is still under investigation.
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