【摘 要】
：
The Hantaan virus (HTNV) is a rodent-borne virus that causes hemorrhagic fever with renal syndrome (HFRS) in China and Asia.HTNV can be transmitted by inhaling aerosolized urine, droppings, or saliva
【机 构】
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Department of Microbiology, School of Preclinical Medicine, The Fourth Military Medical University,
【出 处】
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中国免疫学会第九届全国免疫学学术大会
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The Hantaan virus (HTNV) is a rodent-borne virus that causes hemorrhagic fever with renal syndrome (HFRS) in China and Asia.HTNV can be transmitted by inhaling aerosolized urine, droppings, or saliva of infected rodents, or through rodent bites.Keratinocytes predominate the skin structure, and it has reportedly serves as a replication site for multiple vector-brone viruses.However, little is known about the susceptibility of human skin cells to HTNV infection.We aimed at evaluating if human keratinocytes support HTNV replication and elicit an immune response against HTNV infection.
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