【摘 要】
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Purpose Glucocorticoids(GCs) treatment frequently causes osteoporosis, but currently the precise mechanism in the pathogenesis of glucocorticoid-induced osteoporosis(GIOP) is still not fully elucidate
【机 构】
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Second Affiliated Hospital of Xian Jiaotong University, Department of Orthopaedics
【出 处】
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中华医学会第五次中青年骨质疏松和骨矿盐疾病学术会议
论文部分内容阅读
Purpose Glucocorticoids(GCs) treatment frequently causes osteoporosis, but currently the precise mechanism in the pathogenesis of glucocorticoid-induced osteoporosis(GIOP) is still not fully elucidated.The purpose of the study was to investigate the roles of the local renin-angiotensin system(RAS) of bone in the pathogenesis of GIOP.And we evaluated the efficacy of Angiotensin Ⅱ receptor blockers (ARB) in treatment of GIOP in rabbits.
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