Molecular cloning,characterization and expression analysis of coagulation factor Ⅱ gene in grass car

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户:xiaopp1920
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  Coagulation factor Ⅱ,also named prothrombin,is an important factor of exogenous coagulation system.Studies have shown that it is not only involved in blood coagulation process,but also can be induced a series of inflammatory reaction.It has been studied in mammals and other species,but less research of grass carp (Ctenopharyngodon idella),a commercially important freshwater fish found in China.In this study,the full-length cDNA of grass carp coagulation factor Ⅱ(GcCFⅡ) was cloned using a RACE-Ready cDNA Kit,grass carp were challenged with Grass carp reovirus873(GCRV873).
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