转录组测序揭示人视网膜母细胞瘤Y79细胞及其依托泊苷耐药株之间的化疗药物耐受机制

来源 :2019中国肿瘤学大会 | 被引量 : 0次 | 上传用户：czw6229835

【摘要】

：

目的视网膜母细胞瘤(Retinoblastoma,RB)是最常见的儿科眼内恶性肿瘤。在本研究中,我们利用转录组测序(RNAseq)技术平台,寻找RB Y79 细胞及其依托泊苷耐药细胞株(Y79 etoposidedrug-resistant,Y79/EDR)之间的差异表达基因(Differentially expressed genes,DEGs),阐明RB Y79 细胞的依托泊苷耐药机制并鉴定

【作者】

：

宋文凭邵荣光李亮

【机构】

：

中国医学科学院医药生物技术研究所

【出处】

：

2019中国肿瘤学大会

【发表日期】

：

2019年7期

【关键词】

：

视网膜母细胞瘤依托泊苷耐药 Y79/EDR细胞转录组谱 RNA测序(RNAseq) 差异表达基因(DEGs) ARHGAP9

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转录组测序揭示人视网膜母细胞瘤Y79细胞及其依托泊苷耐药株之间的化疗药物耐受机制

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