Flexible and wearable bionics-sensors,as the most exciting frontier in the field of flexible electronics,have attracted more and more attention due to their unique properties (attachable,wearable,and foldable) and potential applications in consumer electronics,homeland security,and health-related equipment etc.Flexible pressure and strain sensors,as part of artificial electronic skins (E-skins),have attracted increasing massive attention due to their unique advantages in potential applications of health monitoring.Monitoring body physiological signals including blood pressure,heart rate,and wrist pulse presents one of the most convenient methods for non-intrusive diagnosis of diseases.However,currently investigation in detecting human physiological signals by flexible pressure sensors is quite rare,and how to improve the flexibility,sensitivity,response time,and stability is still a big challenge.Here we present our recent works on the formation of free-standing Single-walled Carbon Nanotubes (SWNTs) and Functionalized Graphene Oxide (FGO) ultrathin films,and the construction of transparent and flexible E-skins.With the high conductivity of SWNTs/FGO network and micro-patterned PDMS structures,we developed a facile and low-cost method for fabricating highly flexible pressure sensor arrays,and demonstrated that they are ultra-sensitive (detection limit <0.6 Pa) for detection of super-slight forces with short response time (<10 ms) and excellent stability (>50000 cycles).Furthermore we demonstrated their applications as the wearable devices in monitoring human physiological signals.This work may open a novel and facile method for developing nanomaterials-based flexible nanoelectronic sensing devices,and also may broaden their potential use as cost-effective wearable electronics for prevention of illnesses and prediction of early disease.