ACTA2基因启动子区rs1324551位点多态性与2型糖尿病患者冠脉造影狭窄程度的关联分析

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：DK7531672

【摘要】

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目的:分析ACTA2基因启动子区中rs1324551位点多态性与2型糖尿病患者冠脉造影狭窄程度的关联性.方法:首先在SNP相关的数据库里筛选出ACTA2基因启动子区的8个SNPs.采用病例对照研究,一共251个2型糖尿病对象纳入研究,病例组包括168例血管造影证实血管狭窄超过50％者,对照组包括83例血管狭窄不足50％者.同时收集患者的临床资料和实验室数据,采用基因测序方法对目的SNPs位点进行分

【作者】

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方慧王燕王旭开

【机构】

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重庆市渝中区第三军医大学第三附属医院大坪医院重庆市沙坪坝区第三军医大学基础部

【出处】

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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

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2013年2期

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ACTA2基因启动子区rs1324551位点多态性与2型糖尿病患者冠脉造影狭窄程度的关联分析

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