The intermediate o-quinodimethane(o-QDM),has attracted much attention because it is useful and versatile building blocks in organic synthesis,fullerene chemistry,polymeric materials,medicinal chemistr
Chiral carbocyclic nucleosides,in which the D-ribose portion of the nucleoside is replaced by a cyclopentane moiety,have attracted increasing interest.
The pseudo-trisaccharide allosamidin 1(Scheme 1) is a potent inhibitor of all family 18 chitinases,and it is confirmed to have insecticidal and antifungal activities.
The direct methylenation or methylation of C-H bond and heteroatom-H bond,especially methylenation or methylation of Csp3 -H bond and N-H bond,is one of the most important transformation in organic ch
1,3,4-Oxadiazoles represent a significant class of oxygen-containing heterocycles,which are ubiquitous in various biologically active and pharmaceutically important compounds.
The 2-hydroxy-2,3-dihydrofuran moiety widely exist in many natural products and pharmacological molecules(e.g.,Auranfuron A and B,Siphonarienfuranone,Drimanes,Hydroxyfuranone),1,2 which exhibit excell
Herein,we describe a DABCO-catalyzed [2+2] annulation reaction of allenoates with azodicarboxylates which affords 3-alkylidene-1,2-diazetidines in moderate yields and excellent stereo-and regioselecti
Recently,the direct electrophilic α-cyanation of β-keto esters or amides(1)has been accomplished using active hypervalent iodine cyano reagent(C1)which was prepared in our laboratory.