Inhibition of transcription factor SP1 suppresses colon cancer stem cell growth and induces apoptosi

来源 :The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议) | 被引量 : 0次 | 上传用户：guoqiang113

【摘要】

：

【作者】

：

w.J.Zhang F.Ma Y.Wu X.H.Liu Y.Bai Y.L.Zhang J.D.Wang

【机构】

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Department of Gastroenterology, Nanfang Hospital,Southern Medical University

【出处】

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The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议)

【发表日期】

：

2014年5期

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Aim The transcription factor specificity protein 1 (Sp1) plays a role in development and progression of various human cancers, while cancer stem cells (CSCs) are important in cancer cell selfrenewal and are resistant to chemotherapy and metastasis.This study investigated the role of Spl in colon CSC growth and apoptosis.

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