Flavor additives are added tobacco widely to modify the basic taste of the smoke, and to establish the style of the product.Quality control of tobacco-flavor products has been of increased interest and most of control methods are established by GC or GC-MS.However, the main components of these tobacco additives not only contain volatile compounds, but also contain tobacco additives, which are not volatilizable.HPLC fingerprint is established to take quality control of such unvolatilizable tobacco flavors.It is a indispensability complementary method to GC fingerprint quality control of tobacco-flavor.