【摘 要】
:
Aim: To explore the anticancer effects and underlying mechanism of Gekko ethanol extract (GEE) in vitro and in vivo.Methods: MTT assay was employed to evaluate the anti-proliferative effect of GEE in
【机 构】
:
The Key Laboratory of Pharmacology and Medical Molecular Biology,Medical College,Henan University of
【出 处】
:
The 12th Meeting of the Asia Pacific Federation of Pharmacol
论文部分内容阅读
Aim: To explore the anticancer effects and underlying mechanism of Gekko ethanol extract (GEE) in vitro and in vivo.Methods: MTT assay was employed to evaluate the anti-proliferative effect of GEE in vitro.Hoechst 33258 fluorescence staining was performed to observe morphologic changes nucleus of HepG2 cells; Antitumor properties of GEE in vivo were tested in H22 tumor bearing mice.
其他文献
目的:通过对乏血供肾癌及乏脂肪肾错构瘤的CT能谱特征分析,初步探讨宝石CT能谱成像在两种肿瘤鉴别诊断中的应用价值.方法:回顾性分析经病理证实的41例肾肿瘤患者的CT资料,其中乏血供肾癌21例,乏脂肪肾错构瘤20例.结果:乏血供肾癌在皮质期、实质期的有效原子序数、碘-水浓度、碘-脂肪浓度、标准化碘浓度均低于乏脂肪肾错构瘤,两者间差异均有统计学意义(P<0.05),其中乏脂肪肾错构瘤的脂肪(碘)、水(
目的:探讨低kVp技术在下肢CT血管造影(CTA)低剂量扫描的可行性.方法:选取下肢CTA检查病例98例,实验组50例,对照组48例.实验组使用低kVp 90,对照组使用常规kVp 120.记录两组病例扫描时机器自动显示的扫描长度(L)、容积CT剂量指数(CTDIvol)及剂量长度乘积(DLP),计算有效剂量E值(E).测量并计算腰3椎体水平图像信噪比(SNR)、对比噪声比(CNR)以客观评价图像
随着CTCA应用的增加,检查时的辐射剂量问题渐渐进入人们的视野.通常的CTCA扫描为小螺距的连续螺旋扫描,射线剂量较大,辐射剂量对被辐射人群存在潜在增加癌症发生率的危害性,特别是儿童CT扫描所诱发癌症的概率要高于成年人获得充分的证据支持[4-5].在某发达国家的一项调查中,CT检查占所有放射线检查项目的13%,但导致接受的辐射剂量占患者所接受辐射剂量的70%[6-7]检查时的辐射剂量合理使用低剂量
目的:探讨低剂量扫描技术在儿童副鼻窦病变检查中的临床应用及防护价值.方法:采用西门子公司Siemens Definition AS 64排螺旋CT机.在检查前预先嘱咐患儿在扫描过程中保持静止不动,对于不配合的患儿应待其熟睡或服水合氯醛镇静.患儿仰卧于扫描床上,头部正中线应与CT纵轴定位光标重叠,使听眶线垂直于床面.自上牙槽突到额窦顶部作轴位CT容积扫描.扫描层厚0.1 cm,螺距0.8.扫描野18
目的:本文对我院3.0T Trio梯度故障进行分析与处理,以供同行参考.方法:故障现象:MR在扫描病人腰椎时,发现SE序列可以扫描,但DWI序列无法扫描,将扫描器(SCANNER)重启后,发现头部检查的所有序列包括DWI序列均可以执行扫描,但体部的DWI都不执行,系统提示MR的梯度单元有问题,如下:Gradient Power Amplifier error While scanning.the
Aim: Glycosmis parva leaf extract was reported to have cytotoxicity and antiinflammatory activities with the reduction of COX2 expression in vitro.This study aimed to investigate the effect of ethyl a
Aim: Patients with advanced pancreatic cancer are associated with veous thromboembolism (VTE).tissue factor (TF) is a biomarker in initiation of thrombosis and cancer progression.The aim of this study
Aim: To observe the inhibition effect of high-efficiency immune modulatorsits (HIS) on tumor growth in S180-bearing mice and its regulation in immunologic function and improvement of tumour apoptosis.
Aim: Identification of molecular pathways essential for cancer cells is critical for understanding their underlying biology and designing effective cancer therapies.In this study, effect of expression
Aim: The 4-acetylantroquinonol B (4AAQB) isolated from the mycelium of Antrodia camphorata could inhibit proliferation of hepatocellular carcinoma cells HepG2 with very low IC50.However, the detail mo