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目的：通过对昆明系小鼠1-细胞期受精卵各个细胞周期(G1期、S期、G2期和M期)中蛋白激酶WEE2的表达、活性及其定位进行初步分析,并过表达和降低WEE2,观察小鼠1-细胞期受精卵的卵裂,为进一步研究WEE2对哺乳动物受精卵早期发育调控的机制奠定基础。
蛋白激酶WEE2负调控小鼠1-细胞期受精卵的发育
【摘 要】
：
目的：通过对昆明系小鼠1-细胞期受精卵各个细胞周期(G1期、S期、G2期和M期)中蛋白激酶WEE2的表达、活性及其定位进行初步分析,并过表达和降低WEE2,观察小鼠1-细胞期受精卵的卵裂,为进一步研究WEE2对哺乳动物受精卵早期发育调控的机制奠定基础。
【机 构】
：
辽宁医学院发育生物学教研室,辽宁锦州121001 辽宁医学院生物化学与分子生物学教研室,辽宁锦州1
【出 处】
：
第八届全国医学生物化学与分子生物学、第五届全国临床应用生物化学与分子生物学、2013华东六省一市生物化学与分子生物学联合
【发表日期】
：
2013年2期
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