【摘 要】
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The usability of many high-throughput lab-on-a-chip devices in point-of-care applications is currently limited by the manual data acquisition and analysis p
【机 构】
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CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety,National Center for NanoScience a
【出 处】
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第九届全国微全分析系统学术会议、第四届全国微纳尺度生物分离分析学术会议、2014国际微流控芯片与微纳尺度生物分离分析学术
论文部分内容阅读
The usability of many high-throughput lab-on-a-chip devices in point-of-care applications is currently limited by the manual data acquisition and analysis process,which are labor intensive and time consuming.In this work,inspired by two-imensional(2D)barcodes,we incorporated asymmetric function patterns into a microfluidic array.These function patterns provide quantitative information on the characteristic dimensions of the microfluidic array,as well as mark its orientation and origin of coordinates.We used a computer program to perform automatic analysis for a high-throughput antigen/antibody interaction experiment in 10 s,which was more than 500 times faster than conventional manual processing.Our method is broadly applicable to many other microchannel-based immunoassays.
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