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  5. Cilostazol reduces neointimal hyperplasia by inhibiting superoxide production and expression of lect

Cilostazol reduces neointimal hyperplasia by inhibiting superoxide production and expression of lect

来源 :第11届中国介入心脏病学大会 | 被引量 : 0次 | 上传用户：yizeswing
【摘 要】
：
Background The aim of the study is to investigate whether cilostazol suppresses intimal hyperplasia and to elucidate its mechanism.Methods We examined the effects of cilostazol to the expression of le
【作 者】
：
SU Hua-ke SONG Yao-ming GUO Wen-yun LIU Qi-liang LI Wen-jun 
【机 构】
：
Institute of Cardiovascular Disease,Xinqiao Hospital
【出 处】
：
第11届中国介入心脏病学大会
【发表日期】
：
2013年7期
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Background The aim of the study is to investigate whether cilostazol suppresses intimal hyperplasia and to elucidate its mechanism.Methods We examined the effects of cilostazol to the expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) mRNA and protein, superoxide generation and neointimal hyperplasia of the rat carotid artery after balloon injury.The injury was performed inserting the balloon catheter through the rat common carotid artery and after14 days.
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