Purpose: The purpose of this clinical study was to evaluate the value of computer-assisted design and three dimensional model in mandibular reconstruction by free fibular flap.Methods: 13 mandibular reconstruction procedures using the technique of computer-assisted design and individual 3D-modelby free fibular flaps were performed.The size of the flaps which were used for reconstruction defects ranged between 7 cm and 15cm,and the standard international HCL classification suggested by Jewer et al was used to categorise the defects of mandible.