Purpose: Tertiary lymphoid organs (TLOs) have been described within organ allografts, but whether they promote destructive or beneficial alloimmune response
Background: Mouse dendritic cells (DCs) possessed the tolerogenic potentiality after induced by liver X receptor (LXR) agonist.While the characteristics and
Rationale: X-linked agammaglobulinemia (XLA) is a humoral primary immunodeficiency in which affected patients have very low levels of peripheral B cells.
Background and Purpose: Recently, it was reported that cyclin-dependent kinase 9(CDK9) may be as the critical target for the induction of anti-inflammatory
Background: Rapamycin induces graft tolerance and autophagy in activated T cells.Although, it has been proven that autophagy is required for T cell homeosta
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by chronic synovitis.This study aims to investigate the role of SHH-Gli signaling pa