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  5. Low dose of oleanolic acid protects against lithocholic acid-induced cholestasis in mice:potential i

Low dose of oleanolic acid protects against lithocholic acid-induced cholestasis in mice:potential i

来源 :2015广东省药师周大会 | 被引量 : 0次 | 上传用户：udbnny
【摘 要】
：
Oleanolic acid (OA) is a natural triterpenoid and has been demonstrated to protect against varieties of hepatotoxicants.However recently,OA at high doses was reported to produce apparent cholestasis i
【作 者】
：
Pan Chen Hang Zeng Yongtao Wang Xiaomei Fan Chenshu Xu Rongrong Deng Xunian Zhou Huichang Bi Min Huang 
【机 构】
：
School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou,China
【出 处】
：
2015广东省药师周大会
【发表日期】
：
2014年6期
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　　Oleanolic acid (OA) is a natural triterpenoid and has been demonstrated to protect against varieties of hepatotoxicants.However recently,OA at high doses was reported to produce apparent cholestasis in mice.In this study,we characterized the protective effect of OA at low doses against lithocholic acid (LCA)-induced cholestasis in mice and explored further mechanisms.
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