人偏肺病毒感染发病机制及疫苗研究

来源 :庆祝中国当代儿科杂志创刊15周年大会暨当代儿科论坛 | 被引量 : 0次 | 上传用户:NewComeMan
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全球5岁以下儿童死亡统计784,000 deaths of children < 5 in China 2000,Lancet 2003;.361: 2226-34 Black急性下呼吸道感染·最主要的儿科致死原因:全球每年190万儿童死于ALRI,发展中国家尤显.Williams,B.G.,2002.Lancet Ianfet Dis 2:25-32·中国5岁以下儿童死亡人数约为78万,其中10%-15%死于ALRI.Black Lancet 2003;361:2226-34·病毒仍为ALRI主要病原,多数重症感染继发于呼吸道病毒感染.余春梅,赵晓东等.中华儿科杂志,2010·RSV是世界范围内儿童最常见的呼吸道病原,hMPV紧随其后,目前均无有效疫苗.呼吸道病毒变异将是今后面临的主要问题之一.免疫功能缺陷儿童体 内病毒复制时间明显延长,为病毒变异提供了天然条件.
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