Extensive positive selection on MCPH genesprovides comprehensive insights into genetic basis of brai

来源 :第十一届全国野生动物生态及自然资源学术研讨会 | 被引量 : 0次 | 上传用户:chnlaozhang
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  Cetacean brain size expansion and decrease represents an enigmatic event in mammalian evolution,yet its genetic basis remains poorly explored.All exons of the seven primary microcephaly(MCPH)genes(MCPH1-7,i.e.MCPH1,WDR62,CDK5RAP2,CEP152,ASPM,CENPJ,and STIL)that play key roles in size regulation during brain development were investigated in representative cetacean lineages.
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