Stimulation-sensitive nanocarriers for tumor-targeted drug delivery

来源 :The 6th International Conference on Nanoscience and Technolo | 被引量 : 0次 | 上传用户：wanfan001

【摘要】

：

　　We aimed at obtaining stimulation-sensitive polymeric carriers for tumor targeted drug delivery.A multifunctional polymeric micelle for intracellular drug r

【作者】

：

XintaoShuai[1]DuCheng[2]JingguoLi[2]YiruWang[2]WeiweiWang[3]XingsuYu[3]TinghuiYin[4]RongqinZheng[4]

【机构】

：

School of Chemistry and Chemical Engineering,Sun Yat-sen University,Guangzhou 510275,China

【出处】

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The 6th International Conference on Nanoscience and Technolo

【发表日期】

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2015年期

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　　We aimed at obtaining stimulation-sensitive polymeric carriers for tumor targeted drug delivery.A multifunctional polymeric micelle for intracellular drug release and fluorescent imaging was prepared.In the structural design,an interlayered pH-sensitive "on-off" module was engineered into the micelle to turn the drug release "off" in bloodstream whereas "on" in the acidic lysosomal compartments of cancer cells.

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Stimulation-sensitive nanocarriers for tumor-targeted drug delivery

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