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Objective Tumor can not be completely removed due to the absence of immune storm against tumor.The porcine α 1,3 galactosyltransferase(α 1,3GT)induce the hyperacute rejection by synthesizing Galα 1-3Galβ 1-(3)4GlcNAc-R(α Gal)on the surface of graft endothelial cells(ECs)during xeno-transplantation.