目的:冠状动脉分叉病变植入支架后易形成再狭窄,尽管其形成机理和原因目前仍不十分清楚,但大量的文献表明支架植入引起的血流动力学改变是再狭窄的形成的重要因素之一.在过去较长一段时间里,很多的CFD研究分析了分叉冠脉支架植入过程的血流动力学变化和其主要临床事件.但是大多都是理想化的几何模型,可能存在与临床实际不符的问题.本研究针对真实个体化的冠脉几何模型,虚拟植入支架后,分析支架后即时血流动力学参数对再
主动脉缩窄是第五大常见的先天性心血管疾病,占先天性心血管病的6％-8％.主要表现上肢高血压,而下肢脉弱或无脉,双下肢血压明显低于上肢(ABI＜0.9),听诊狭窄血管周围有明显血管杂音.今我院高血压病房收治主动脉缩窄所致完全闭塞误诊为嗜铬细胞瘤一例,患者为40岁男性,12年前因突发言语不利、视物模糊就诊于当地医院,测血压170/100 mmHg,颅脑CT提示脑梗塞,给予相应治疗后出院,血压多维持在1
Background Pulmonary hypertension is a pathophysiologic syndrome with high morality and disability.Pulmonary hypertension is associated with intracellular membrane trafficking in which the protein Sna
Background Spinal cord and vagus nerve stimulation were demonstrated to reduce the incidence of ventricular arrhythmias (VAs), somatic nerve stimulation was reported to improve myocardial ischemia and
Objective We examined the role of renal denervation on the inducibility of AF in dogs with pacing-induced HF.Background Atrial fibrillation (AF) and heart failure (HF) are co mmon interrelated conditi
Purpose In previous studies, it has been shown that recombinant human neuregulin-1 (rhNRG-1) is capable of improving the survival rate in animal models of doxorubicin (DOX)-induced cardiomyopathy
Objective To investigate the effects of sildenafil on the remodeling of pulmonary arterial and TNF-alpha expression in model induced by monocrotaline in pneumonectomized rats.
Objective To investigate transplantation of MSCs in treatment of DCM on the feasibility of TGF-β1, AT1, CYP11B2 and myocardial collagen expression.Method 1.Rate were injected ADR to build DCM model.
Aim Renal ischemia/reperfusion (I/R) injury is a co mmon clinical disease.We have known that NO-signal transduction has an important effect on renal I/R injury.
Rationale Transplantation of stem cells into damaged hearts has had modest success as a treatment for ischemic heart disease.One of the limitations is the poor stem cell survival in the diseased micro