The Lycopodium alkaloids are a family of structurally complex natural products, which have provoked long-term interests in their total syntheses due to their unique and fascinating architectures, as well as significant biological activities.Inspired by the intriguing biogenetic pathways for both fawcettimine and serratinine-type Lycopodium alkaloids, we have been engaged in their total syntheses since 2009.[1] Herein, we would like to report our latest endeavors toward the total syntheses of huperzine Q and lycopladine D which were enabled by a number of cascade reactions.