【摘 要】
：
Aims:To observe the clinical efficacy of anti-HBV-DC vaccine,the dendritic cells originating from peripheral blood mononuclear cells(PBMC) sensitized by HBsAg,in combination with thymosin-α 1,in the H
【机 构】
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Southern Medical University Renkang Hospital Gastroenterology and Hepatology Center,China;Guangzhou
【出 处】
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中华医学生物免疫学会第二届学术年会
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Aims:To observe the clinical efficacy of anti-HBV-DC vaccine,the dendritic cells originating from peripheral blood mononuclear cells(PBMC) sensitized by HBsAg,in combination with thymosin-α 1,in the HBeAg negative patients of chronic hepatitis B virus(HBV) infection.Methods:24 inactive HBsAg carriers and 25 chronic hepatitis B(CHB) patients were recruited in the trial.PBMCs obtained from 50ml of heparinized peripheral blood through density gradient centrifuge and adherence method were proliferated under the induction by GM-CSF and IL-4,and sensitized with the 50μig HBsAg.
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