Activation mechanism of an inhibitory neurotransmitter GPCR

来源 :The 10th Chinese Symposium on Calcium Signaling(第十届全国钙信号和细胞功 | 被引量 : 0次 | 上传用户:lxl
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The inhibitory neurotransmitter γ-aminobutyric acid (GABA) activates both ionotropic GABAA receptors and metabotropic GABAB receptors.The GABAB receptor belongs to class C GPCR, represents the promising drug target for the treatment of epilepsy, pain, drug addiction,anxiety and depression.
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