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objective: To study the prevalence of transfusion transmitted virus (TTV) in Xinjiang patients with tuberculosis.Methods: Sera from patients with tuberculosis were tested by nested polymerase chain reaction(nPCR) assay for the presence of TTV-DNA.Results: The total detection rate of TTV DNA in those 229 patients with tuberculosis was 22.3% (51/229) and that in contral population was 7.8% (14/180).The TTV positive rate was 36.8% (21/57) in the aged patients with tuberculosis and higher than that (18%) in the yanger patients with tuberculosis (23/128) (P<0.05).There was no relationship of TTV infection between sex and ethnic groups of patients with tuberculosis(P>0.05).Conclusion: The higher risk population of infection rat of TTV is the patients with tuberculosis in Xinjiang.The aged patients is TTV supper-infection with tuberculosis in Xinjiang.