【摘 要】
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Objective To study the changes of brain water diffusion and cerebral haemodynamics of cortical areas using magnetic resonance imaging (MRI) in canine models of cardiac arrest (CA) and restoration of s
【机 构】
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Department of Emergency,The First Affiliated Hospital,Sun Yat-sen University,58,Zhongshan Road Ⅱ,Gua
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Objective To study the changes of brain water diffusion and cerebral haemodynamics of cortical areas using magnetic resonance imaging (MRI) in canine models of cardiac arrest (CA) and restoration of spontaneous circulation (ROSC).The secondary study objective was to evaluate whether MRI can be used to observe haemodynamic disorders in brain microcirculation.Methods CA was induced in six beagle dogs using electrical stimulation followed by resuscitation to spontaneous circulation 3 min later.The dogs were scanned using MRI for echo planar, diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) with injection of Gd-diethylene triamine pentaacetic acid (DTPA) prior to induction of CA and 3 days after ROSC.
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