Protective effects of luteolin-7-O-glucoside from Dracocephalum Rupestre Hance on doxorubicin-treate

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户:zhaobaodong2006
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Aim: Previous research has shown that luteolin-7-O-glucoside pretreatment had a significant protective effect against doxorubicin-induced cyotoxicity.It could reduce cardiomyocyte apoptosis, intracellular calcium overload, leakage of creatine kinase and lactate dehydrogenase, and reactive oxygen species generation induced by doxorubicin.But the mechanisms are unclear.
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