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Background: The hospital employees health is critical to the safety in healthcare services;however,the information concerning their psychological issues,especially in depressive disorder,is still very limited.Aims: The aims of this study are to explore the depression and its related factors among hospital employees.Methods: We used a cross-sectional correlation design with purposive sampling to recruit 219 hospital employees who have more than one year work history by July 2010 at a southern Taiwan hospital.A structured questionnaire was applied during their cyclic health check-up to collect information on demographic statics,working characteristics and information provided by the Chinese version of Taiwanese Depression Questionnaire.Data were analyzed by descriptive statistics,independent t-test,chi-square test,and multiple logistic regression.Results: The depression prevalence in this study population was 16.9% (37/219).The hospital employees with sleep disturbance (adjusted odds ratio[AOR],4.34;95% CI:3.14-5.22),lower job satisfaction (AOR=1.16;95% CI: 1.07-1.25),and having longer time of computer usage (AOR=2.14;95% CI: 1.32-3.14) showed a significantly higher risk of depression compared with those without these conditions.Conclusion: Our findings may be beneficial in identifying the prevalence and pinpointing those groups with a higher predisposition of having depression,which will allow the early assessment of psychological health status as well as provision of workplace health promotion system for hospital employees.