Objective Loss of synaptic spine has been considered the earliest events of cerebral ischemia and generally assumed to be associated with the subsequent brain damages,but its underlying molecular mech
The Huntington disease(HD)protein,huntingtin(Htt),is essential for early development.Since suppressing mutant htt expression becomes an important approach to treat HD,understanding the normal function
Secondary generalized seizures(sGSs)are a major source of disability in temporal lobe epilepsy(TLE),but the underlying cellular/circuit mechanisms remain unclear.