A strain-relief structure was proposed for fabricating flexible spin valves by combining the strain-engineered periodic wrinkling and the parallel ribbons on PDMS substrates.The strain-relief structure can accommodate the biaxial strain accompanying with stretching operation(the uniaxial applied tensile strain and the induced transverse compressive strain due to the Poisson effect),thus significantly reducing the influence of the residual strain on the giant magnetoresistance(GMR)performance.