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5. THE EFFECT OF CORE-SHELL PARTICLES ON CHROMATOGRAPHIC DETERMINATION AND OPTIMIZATION OF DUTASTERIDE

THE EFFECT OF CORE-SHELL PARTICLES ON CHROMATOGRAPHIC DETERMINATION AND OPTIMIZATION OF DUTASTERIDE

来源 :43rd International Symposium on High Performance Liquid Phas | 被引量 : 0次 | 上传用户：Z_PEPSI

【摘 要】

：

Dutasteride(DUT),selective inhibitor of both type 1 and type 2 isoforms of 5α-reductase enzyme that converts testosterone to 5α dihydro testosterone which is responsible for enlargement of prostate,ch

【作 者】

：

Bengi Uslu Aysen Gumustas Mehmet Gumustas B.Bugra Barut Sibel A.Ozkan 

【机 构】

：

Ankara University,Faculty of Pharmacy,Department of Analytical Chemistry,Tandogan,06100 Ankara,Turke

【出 处】

：

43rd International Symposium on High Performance Liquid Phas

【发表日期】

：

2015年7期

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论文部分内容阅读

Dutasteride(DUT),selective inhibitor of both type 1 and type 2 isoforms of 5α-reductase enzyme that converts testosterone to 5α dihydro testosterone which is responsible for enlargement of prostate,chemically it shown as(5α,17β)-N-{2,5 bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1ene-17-carboxamide.

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