Exogenousparathyroidhormone-relatedpeptidepromotesfracturehealinginLepr(-/-)mice

来源 :中华医学会第十七届骨科学术会议暨第十届COA国际学术大会 | 被引量 : 0次 | 上传用户:zzy705664916
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  Diabeticosteoporosiscontinuestosurgeworldwide,increasingtheriskoffracture.Wehavepreviously demonstratedthathaploinsufficiencyofendogenousparathyroidhormone-relatedpeptide(PTHrP)impairs fracturehealing.However,whetheranexogenoussupplyofPTHrPcanrepairbonedamageandaccelerate fracturehealingremainsunclear.
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1.Ourpreviousstudieshavedemonstratedthatthathaploinsufficiencyofendogenousparathyroidhormonerelated peptide(PTHrP)impairsbonefracturehealing.However,itisunclearwhetherexogenouss