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5. A genome-scale dynamic metabolic model of Streptomyces tsukubaensis NRRL18488 to predict the targets

A genome-scale dynamic metabolic model of Streptomyces tsukubaensis NRRL18488 to predict the targets

来源 :2015代谢工程高峰会议(Metabolic Engineering Summit 2015) | 被引量 : 0次 | 上传用户：zdf657094142

【摘 要】

：

FK506 is an important immunosuppressant,which is firstly discovered and isolated from S.tsukubaensisNRRL18488.However,an important limitation to its applications is the low titer of FK506 in the origi

【作 者】

：

Cheng Wang Jiao Liu Haishan Qi Jianping Wen 

【机 构】

：

School of Chemical Engineering and Technology,Tianjin University,Tianjin,300072,China

【出 处】

：

2015代谢工程高峰会议(Metabolic Engineering Summit 2015)

【发表日期】

：

2015年3期

【关键词】

：

Target prediction FK506 GS-DFBA Streptomyces tsukubaensis NRRL18488 

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　　FK506 is an important immunosuppressant,which is firstly discovered and isolated from S.tsukubaensisNRRL18488.However,an important limitation to its applications is the low titer of FK506 in the originalproducer strain.

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