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Biofilms are microbial communities that are attached to a solid surface using extracellular polymeric substances.Motility and initial attachment mediated by flagella are required for biofilm formation.Therefore,blocking the motility of flagella is a potential strategy to inhibit biofilm formation.In this study,single-stranded DNA aptamers specific to the Salmonella choleraesuis were selected after 14 cycles of the systematic evolution of ligands by exponential enrichment(SELEX).