Zebrafish Cadherin 5 negatively regulates mobilization of aorta-gonad-mesonephros-derived hematopoie

来源 :第三届全国发育生物学大会 | 被引量 : 0次 | 上传用户：eline77

【摘要】

：

【作者】

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Ping Meng Yongxiang Liu Xiaohui Chen Wenqing Zhang Yiyue Zhang

【机构】

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Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Guangdong Higher Educa

【出处】

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第三届全国发育生物学大会

【发表日期】

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2016年8期

【关键词】

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Cadherin 5 (Cdh5) cMyb HSC trafficking zebrafish

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　　Establishment of HSC pool depends on the stem cell proper formation,maturation and mobilization to defined hematopoietic tissues in vertebrates.However,the molecular basis underlying embryonic HSC mobilization is poorly understood.The adhesion molecule cadherin 5 (cdhS) gene expression has been suggested to participate in HSC migration,but functional data supporting its direct involvement in embryonic HSC mobilization is lacking.

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Zebrafish Cadherin 5 negatively regulates mobilization of aorta-gonad-mesonephros-derived hematopoie

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