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目的:探讨体外受精-胚胎移植中发生异位妊娠的危险因素。方法:回顾分析中山大学附属第二医院生殖中心2001年6月~2008年10月接受体外受精-胚胎移植治疗后42例异位妊娠患者的临床资料。结果:共有779个周期获得妊娠,42例为异位妊娠(5.39%),其中宫内宫外同时妊娠10例(23.81%),异位妊娠组与正常妊娠组比较,既往发生宫外孕的比率较高、HCG日内膜平均厚度较薄、移植过程困难比率高。结论:既往宫外孕发生史、HCG日内膜厚度、移植过程困难可能是体外受精-胚胎移植后发生异位妊娠的高危因素。
Objective: To explore the risk factors of ectopic pregnancy during in vitro fertilization-embryo transfer. Methods: The clinical data of 42 patients with ectopic pregnancy after IVF-ET treatment from June 2001 to October 2008 in the Second Affiliated Hospital of Sun Yat-sen University were retrospectively analyzed. Results: A total of 779 cycles of pregnancy were obtained, 42 cases of ectopic pregnancy (5.39%), of which 10 cases (23.81%) were intrauterine uterine simultaneous pregnancy, ectopic pregnancy compared with normal pregnancy group, compared with the previous ectopic pregnancy rate High, HCG endometrial average thickness is thin, high difficulty in the process of transplantation. CONCLUSION: The history of previous ectopic pregnancy, HCG endometrial thickness and difficulty of transplantation may be the risk factors of ectopic pregnancy after in vitro fertilization-embryo transfer.