Porous polymers have been accepted as an effective material for high specific surface area in favor of mass transfer1, 2.The hollow porous molecularly imprinted polymers (MIPs) were prepared by multi-step seed swelling polymerization using cholesterol as the template molecule, and appeared single-hole hollow structure characterized by SEM and TEM, which were applied as solid-phase extraction sorbent for selective determination of Sudan Ⅰ in chilli sauce samples.The porous MIPs with high specific surface area (proved by nitrogen adsorption experiments) and high thermal stability (were not decompose less than 400 ℃ using DSC), exhibited much higher binding capacity than irregular solid MIPs prepared by bulk polymerization, because of most of the binding site were located in the surface of microsphere facilitating template removal and mass transfer.Good recoveries at three spiked levels were ranged from 90.9%-103.3% with the precision of 1.85%-4.68% in chilli sauce samples.The hollow porous MIPs with high selectivity, high stability could be applied for high selective determination of Sudan in complicated samples.