The age of parenthood has been steadily increased during the last decades, so it is very important to study the influence of aging on reproductive outcomes.The adverse effect of female aging has been widely investigated.In contrast, the impact of advanced paternal age has been comparatively less studied and there was no consensus on its role in reproduction.In our study weinvestigate the effect of male age on the reproductive outcomes of in vitro fertilization (IVF).We retrospectively analyzedthe data of IVF cycles in the Reproductive Medicine Center of the Third Affiliated Hospital of Guangzhou Medical Universitybetween January 2007 and October 2013.The samples were divided into three groups according to female age(<30, 30-34,35-38)and each group was subdivided into six groups according to the male age(<30, 30-32, 33-35,36-38, 39-41, ≥42).The main outcomes were embryo quality, fertilization rate, implantation rate, pregnancy rate, miscarriage rate.There were totally 9991 cycles included in this study.Female age was <30 years in 3327 cycles, 30-34 years in 4587 cycles and 35-38 years in 2077 cycles.There was no statistical significance when considering the fertilization rate, number of useful embryos, number of high-quality embryos and miscarriage rate (P >0.05).Chi-squared analysis revealed no statistical difference regarding implantation rate and pregnancy rate in different male age groups when female age was <30 and 35-38 years (P >0.05).However, implantation rate and pregnancy rate significantly decreased with male age when woman was 31-34 years (P <0.05).Our study concluded that male age had no impact on fertilization rate, embryo quality of cleavage stage and miscarriage rate but negatively affected implantation rate and pregnancy rate when woman was 31-34 years.