No association between catechol-O-methyltransferase Val158Met polymorphism and susceptibility to pre

来源 :2013中国妇产科学术会议 | 被引量 : 0次 | 上传用户:zyff1985
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Background Catechol-O-methyltransferase (COMT) is a key enzyme involved in catecholamine and estrogen degradation and has recently been ascribed a role in development of preeclampsia.The COMT gene contains a functional polymorphism, Val158Met, which results in 3-4 fold difference in the enzyme activity.A case-control study was conducted to investigate the impact of this polymorphism on the risk ofpreeclampsia in northeast Chinese population.
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