@@ Cassava (Manihot esculenta Crantz) accumulates a lot of starch in its storage roots that can be processed to food, feed, modified starches and bio-fuels. The high yield potential and robustness against unfavorable environmental conditions make cassava suitable crop for marginal lands, which will not highly compete with other food crops on arable lands. There are several key biological constraints in cassava for bio-industrial development. For example, the post-harvest physiological deterioration (PPD) of cassava storage roots is the biggest disadvantage during starch and bio-ethanol process world-wide; Different types of starches from cassava are also demanding by starch companies; Stable and high yield under different environmental conditions is also required. these constraints, but with limited success due to the nature of heterozygousity and inbreeding depression in cassava. New biotechnological tools can change this