The aims of present study were to analysis of chemical compositions and evaluate anti-Candida activity of Dittrichia gravolence essential oil.The composition of the hydrodistilled essential oil from aerial parts of Dittrichia graveolens (L.) Greuter grown in Iran was investigated by GC/MS.The major components, among the identified 22, were 1,8 Cineol (54.89%), P-Cymen (16.2%), [beta]-pinene (6.94%) and Borneol (5.44%).