Objective:To compare the clinical effects Chinese polygeline with HAES-steril as the priming solution of extracorporeal circulation.Methods:60 adult patients with extracorporeal circulation were randomly divided into two groups.The experiment group primes with polygeline and lactic acid Ringers solution.The control group primes with HAES-steril and lactic acid Ringers solution.Results:1.Osmotic pressure in the Chinese polygeline group is higher than that in the control group; The urine volume in the Chinese polygeline group is more than that in the control group; The concentration of Mg2+ after heart beating in the experiment group is lower than that in the control group; The concentration of potassium has no significant difference in the two groups.2.