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5. Discovery of New Substrates for LuxAB Bacterial Bioluminescence

Discovery of New Substrates for LuxAB Bacterial Bioluminescence

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：zhaojiagu

【摘 要】

：

In this research,four novel substrates with long half-time have been designed and synthesized successfully(Scheme 1).After biological evaluation,all of them showed apparent bioluminescence emission in

【作 者】

：

Tianyu Jiang Minyong Li 

【机 构】

：

Department of Medicinal Chemistry,Key Laboratory of Chemical Biology(MOE),School of Pharmaceutical S

【出 处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

bacterial bioluminescence new long chain aliphatic aldehydes luxAB imaging 

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　　In this research,four novel substrates with long half-time have been designed and synthesized successfully(Scheme 1).After biological evaluation,all of them showed apparent bioluminescence emission in combination with E.coli that transfected with plasmid carrying luxAB [1,2].

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