【摘 要】
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Background, Motivation and Objective Quantitative ultrasound (QUS) methods were developed to detect metastatic regions in freshly excised sentinel lymph nodes from breast-cancer patients using a 26-MH
【机 构】
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F. L. Lizzi Center for Biomedical Engineering, Riverside Research, USA
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Background, Motivation and Objective Quantitative ultrasound (QUS) methods were developed to detect metastatic regions in freshly excised sentinel lymph nodes from breast-cancer patients using a 26-MHz transducer. These QUS methods use a Gaussian form factor to model ultrasound scattering. In this study, quantitative acoustic microscopy (QAM) at 250 MHz was performed to obtain 2D maps of speed of sound (c), attenuation (A) and acoustic impedance (Z) of nodal tissue microstructure with a spatial resolution of 7 μm. These maps were used to develop new ultrasound-scattering models to enhance the sensitivity and specificity of QUS methods.
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