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A novel method for preparing an injectable hydrogel made from hyaluronic acid/human-like collagen/hydroxyapatite was developed and studied in this paper.First, the micron-grade.hydroxyapatite was made by chemical coprecipitation method:different ratio of CaCl2, Na2HPO4 and cetyltrimethylammoninm bromide were mixed intensely and reacted in ultrapure water under different pH and temperature.