Capillary electrophoresis (CE) has been a rapid developed analytical technique for chromatographic separation [1].However,adsorption of biomacromolecules,especially proteins onto fused-silica capillary walls is one of the major challenges of CE [2,3].In order to minimize protein adsorption onto the capillary surface,surface modification with capillary coatings has become a research hotspot [4,5].Nevertheless,the preparation process of covalent coatings is usually complicated which includes multi-steps such as capillary pretreatment,introducing coupling agents,and inserting target coating reagents [6,7].